Relevant Publications
2024
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2023
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Suzuki, I., et. al. Verification of the seizure liability of compounds based on their in vitrofunctional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivoextrapolation to cerebrospinal fluid concentration. Toxicol Appl Pharmacol., 2023
Bartmann, K., et. al. A Human iPSC-based In VitroNeuralNetwork Formation Assay to Investigate Neurodevelopmental Toxicity of Pesticides. ALTEX, 2023
2022
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Ishibashi, Y., et al, Responses to antibiotics in human iPSC-derived neurons based on the clinical antibiotic associated encephalopathy classification. J. Toxicol. Sci., 2022
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Pediaditakis, I., et al., A Microengineered Brain-Chip to Model Neuroinflammation in Humans. iSCIENCE, 2022
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TCW, J., et. al. Cholesterol and matrisome pathways dysregulated in astrocytes and microglia. Cell, 2022
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Zaer, H., et. al. Non-Ablative Doses of Focal Ionizing Radiation Alters Function of Central Neural Circuits. Brain Stimulation, 2022
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2021
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Saavedra, L., et. al. Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures. Toxicol Sci., 2021
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2020
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Tukker, A., et. al. Towards Animal-Free Neurotoxicity Screening: Applicability of hiPSC-Derived Neuronal Models for In Vitro Seizure Liability Assessment. ALTEX, 2020
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Soscia, D., et al. A flexible 3-dementional micro electrode array for in vitro brain models. Lab Chip, 2020
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2017
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Yang, N., et al. Generation of pure GABAergic neurons by transcription factor programming. Nat Methods, 2017
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2016
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Yi, F., et al. Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons. Science, 2016
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2015
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Pak, C., et al. Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1. Cell Stem Cell, 2015
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2013
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Zhang, Y., et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron, 2013
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